Comparison of Same Day Polyethylene Glycol Regimen Vs Split Dose Polyethylene Glycol Regimen for Colonoscopy

Colonoscopy is a procedure which depends upon the quality of bowel preparation. Polyethylene glycol(PEG) is commonly used laxative for bowel preparation .The method of PEG administration affects the quality of bowel preparation. We designed this single-blinded randomized controlled trial to evaluate same day PEG regime vs split dose PEG regime in patients undergoing colonoscopy. METHOD: Total of 156 patients taken for the examination. They were divided randomly in two groups A & B. The patients in the group A (same day group) took 2 L of PEG between 6:00 AM and 8:00 AM on the same day of colonoscopy. The patients in the other group B ( split dose group ) took 1L of PEG between 6:00 PM and 8:00 PM on the preceding day and another liter between 6:00 AM and 8:00 AM on the day of colonoscopy. These patients had to stay in hospital for about 24 hours.The accuracy of preparation was assessed on Boston Bowel Preparation Scale (BBPS). A sum total of ≤ 5 points shows poor bowel preparation & ≥ 8 shows very good bowel preparation. Side effects were recorded by asking symptoms of nausea ,vomiting ,abdominal pain & bloating. Results: In same day dose group, 62 patients were having BPPS preparation score of >8 . While in second split dose group 64 patients were having BPPS preparation score >8. Chi square test revealed that there was no significant difference in BPPS score between both groups. However there was significant difference in patient satisfaction and willingness to repeat the same procedure between both groups. . Group A same dose regime were more satisfied & willing to repeat the procedure. They reported less interference in their sleep . Conclusion: Same- day morning PEG regime should be used which is more easy & tolerable for our patients population and its efficacy is same as other regimes for adequate bowel preparation.