Enantioselectivity in Odor Perception: Synthesis and Olfactory Properties of Iso-β-Bisabolol, a New Natural Product

Authors :: Wilhelm Pickenhagen
Gerhard Schmaus
Norbert A. Braun
Manfred Meier
Bernd Hölscher
Source :: Helvetica Chimica Acta. 86:2698-2708
Publication Year :: 2003
Publisher :: Wiley, 2003.
Abstract: The odorous trace constituent iso-β-bisabolol (4) was isolated from East Indian and Western Australian sandalwood oil and synthesized by using the (E/Z)-triene 12 (iso-γ-bisabolene) as a key intermediate. Only one of four stereoisomeric forms of 4, (6R,7R)-4a, is odor active, having a strong floral, muguet-like, very pleasant scent.

Subjects :: Odor perception
Natural product
Stereochemistry
Organic Chemistry
East indian
Biochemistry
Catalysis
Inorganic Chemistry
chemistry.chemical_compound
chemistry
Odor
Australian Sandalwood Oil
Drug Discovery
Organic chemistry
Physical and Theoretical Chemistry
Bisabolol

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