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Labeling Monoclonal Antibody with α-emitting 211At at High Activity Levels via a Tin Precursor
- Source :
- Cancer Biotherapy and Radiopharmaceuticals. 35:511-519
- Publication Year :
- 2020
- Publisher :
- Mary Ann Liebert Inc, 2020.
-
Abstract
- Background: In a previous clinical study, the authors evaluated the potential of antitenascin C monoclonal antibody (mAb) 81C6 labeled with 211At via the prosthetic agent N-succinimidyl 3-[211At]as...
- Subjects :
- 0301 basic medicine
Pharmacology
Cancer Research
medicine.drug_class
Targeted Radiotherapy
medicine.medical_treatment
chemistry.chemical_element
General Medicine
Monoclonal antibody
Molecular biology
Clinical study
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Oncology
chemistry
030220 oncology & carcinogenesis
Radioimmunotherapy
medicine
High activity
Radiology, Nuclear Medicine and imaging
Tin
α particles
Subjects
Details
- ISSN :
- 15578852 and 10849785
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Cancer Biotherapy and Radiopharmaceuticals
- Accession number :
- edsair.doi...........2afe6745aa3f23b9e93beb2ad26c6130
- Full Text :
- https://doi.org/10.1089/cbr.2019.3204