Back to Search
Start Over
Immunohistochemical staining as supportive diagnostic tool for pseudomyxoma peritonei arising from intraductal papillary mucinous neoplasm: A report of two cases and literature review
- Source :
- Pancreatology. 20:1226-1233
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Background/Objectives Pseudomyxoma peritonei (PMP) arising from an intraductal papillary mucinous neoplasm of the pancreas (IPMN) is a rare condition. The diagnosis of IPMN as the origin of PMP is mainly inferred from the clinical course and the exclusion of PMP from other organs. The pathological diagnosis has not yet been established. To evaluate the usefulness of immunohistochemical staining for the diagnosis of the primary lesion of PMP as IPMN. Methods There are 2 cases of PMP arising from IPMN between March 2010 and December 2019 at National Center for Global Health and Medicine. A PubMed search that reported PMP arising from IPMN identified 16 additional cases. Diagnostic methods and clinicopathological features of 18 cases were compared. Results Four cases including our two cases used immunohistochemical staining for the diagnosis of PMP arising from IPMN. The correspondence of the immunohistochemical staining between PMP and IPMN was shown in the three cases including previously reported two cases and one of our two cases to identify the primary lesion of PMP as IPMN. In addition, we revealed that the comparison of the immunostaining pattern of PMP with the representative immunostaining pattern of the candidate primary lesions is helpful for the diagnosis of the primary lesion of PMP. Conclusions Immunohistochemical staining is helpful to identify the primary lesion of PMP as IPMN.
- Subjects :
- Pathology
medicine.medical_specialty
Diagnostic methods
endocrine system diseases
Hepatology
Intraductal papillary mucinous neoplasm
business.industry
Endocrinology, Diabetes and Metabolism
Gastroenterology
Clinical course
medicine.disease
medicine.anatomical_structure
medicine
Pseudomyxoma peritonei
Immunohistochemistry
Pancreas
business
Pathological
Immunostaining
Subjects
Details
- ISSN :
- 14243903
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Pancreatology
- Accession number :
- edsair.doi...........2a5214e14ff097a2e20580000cc86dfb