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A Convenient Synthesis of Rivaroxaban from (S)-Epichlorohydrin

Authors :
Ales Halama
Radim Krulis
Jan Rymes
Source :
Organic Preparations and Procedures International. 52:201-211
Publication Year :
2020
Publisher :
Informa UK Limited, 2020.

Abstract

Rivaroxaban 1 is an oxazolidinone derivative that is the first representative of a new series of anticoagulants,1,2 and it was soon followed by apixaban, betrixaban and darexaban.3–5 It is an oral,...

Subjects

Subjects :
chemistry.chemical_compound
Rivaroxaban
chemistry
Betrixaban
Organic Chemistry
medicine
Epichlorohydrin
Apixaban
Combinatorial chemistry
Derivative (chemistry)
medicine.drug

Details

ISSN :
19455453 and 00304948
Volume :
52
Database :
OpenAIRE
Journal :
Organic Preparations and Procedures International
Accession number :
edsair.doi...........297ad825fa120b3d20cec6ba88cf5ae6

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