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Comparison between Essential Vocal Tremor and Dystonic Vocal Tremor Treated with Botulinum Toxin and Propranolol
- Source :
- Otolaryngology–Head and Neck Surgery. 151
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Objectives:Determine and compare the response to treatment with intramuscular botulinum toxin and oral propranolol on vocal tremors, essential and dystonic.Methods:Randomized clinical trial between January 2012 and September 2013. Fifteen patients with vocal tremor were divided into 2 groups: essential and dystonic vocal tremor. Both groups were treated with botulinum toxin in thyroarytenoid muscle (15 units of Dysport unilaterally) and propranolol (80 to 120 mg daily) at different times. Time to “wash out” after injection of 6 months and after propranolol 2 months. Patients underwent self-assessment of vocal improvement, nasofibroscopy larynx, perceptual, and acoustic analysis of voice before and after each treatment. Data were compared according to the type of tremor and treatment and subjected to statistical analysis (significance level of .05).Results:There was statistically significant improvement in perceptual measure of vocal instability in patients with dystonic tremor after treatment with botuliu...
- Subjects :
- Larynx
Dystonic vocal tremor
medicine.medical_specialty
business.industry
Vocal tremor
Propranolol
Botulinum toxin
law.invention
Surgery
medicine.anatomical_structure
Otorhinolaryngology
Randomized controlled trial
law
Anesthesia
Medicine
Thyroarytenoid muscle
Statistical analysis
business
medicine.drug
Subjects
Details
- ISSN :
- 10976817 and 01945998
- Volume :
- 151
- Database :
- OpenAIRE
- Journal :
- Otolaryngology–Head and Neck Surgery
- Accession number :
- edsair.doi...........29156276c7288dc80542c8d34cf05b5c