ChemInform Abstract: Copper Catalyzed C-O Bond Formation via Oxidative Cross-Coupling Reaction of Aldehydes and Ethers

A practical and efficient construction of C-O bonds via oxidative cross-coupling reaction of aldehydes and ethers has been realized under open air. When 2 mol% copper was used as the catalyst, various α-acyloxy ethers were obtained with up to 93% isolated yield.