Coherent scatter computed tomography: a novel medical imaging technique

Fan-beam coherent scatter computed tomography (CSCT) is a novel X-ray based imaging method revealing structural information of tissue under investigation. The source of contrast is the angular-dependent coherent scatter cross-section, which is determined by the molecular structure. In this work a phantom consisting of water, tricalcium phosphate, collagen and fat was used to investigate the contrast resolution of these four tissue constituents. Scatter projections were measured in fan-beam 3rd generation CT-geometry using an experimental demonstrator set-up equipped with a 4.5 kW DC power X-ray tube and photon-counting detectors. Reconstruction was performed using two algorithms, one based on algebraic reconstruction technique (ART) and the other based on filtered back-projection (FBP). The reconstruction results of the two techniques are compared. Furthermore, scatter functions of the four components were extracted from the 3D data sets and compared to previous measurements. The applicability of this technique for medical diagnosis is discussed.