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Hydroxamate inhibitors of human gelatinase B (92 kDa)

Authors :
Tricia A. Pulvino
Robert C. Wahl
Madhusudhan Reddy Gowravaram
Ewell R. Cook
Bruce E. Tomczuk
Arup K. Ghose
Alan M. Mathiowetz
Daniel Delecki
Jeffrey Johnson
James A. Gainor
Source :
Bioorganic & Medicinal Chemistry Letters. 5:349-352
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

Gelatinase B is potently inhibited by peptide hydroxamates, including molecules that have a R 1 ′ group which is larger than the side chains of the natural amino acids.

Details

ISSN :
0960894X
Volume :
5
Database :
OpenAIRE
Journal :
Bioorganic & Medicinal Chemistry Letters
Accession number :
edsair.doi...........2763906b1c6dba6d82d224cac1fbec74
Full Text :
https://doi.org/10.1016/0960-894x(95)00033-p