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Impact dosimétrique de la pose d’un espaceur rectal dans le traitement de cancer de la prostate localisé par irradiation en conditions stéréotaxiques
- Source :
- Cancer/Radiothérapie. 25:237-241
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Purpose Stereotactic body radiotherapy (SBRT) of prostate cancer is associated with rectal toxicities, which can be reduced by using a hydrogel spacer. The object of this retrospective study was to show the feasibility of spacer placement under local anesthesia and utility of hydrogel spacer to reduce the dose to the rectal wall. Material and methods We collected data from all patients with localised prostate cancer treated with SBRT (40Gy in 5 fractions) between 2018 and 2020. A hydrogel spacer (SpaceOAR®) was placed depending on the availability of the product. We collected dosimetric data for target volumes and organs at risk. We calculated mean values, which were compared using non-parametric tests. Results Among 35 patients, mean age was 75 years. Seventeen had a spacer placed, with a mean space created of 10mm. No complication was reported during the intervention. High doses to the rectal wall were significantly lower in spacer group (V38: 0.39 cm3 vs. 0.72 cm3; P=0.02). PTV were better covered in spacer group (P=0.07). Doses to the bladder wall were similar in both groups. Conclusion Spacer procedure under local anesthesia was well tolerated. Hydrogel spacer allowed to reduce doses to the rectum while improving PTV coverage.
- Subjects :
- business.industry
medicine.medical_treatment
Rectum
Mean age
medicine.disease
Radiation therapy
03 medical and health sciences
Prostate cancer
0302 clinical medicine
medicine.anatomical_structure
Oncology
Rectal wall
030220 oncology & carcinogenesis
medicine
High doses
Radiology, Nuclear Medicine and imaging
Local anesthesia
Nuclear medicine
business
Stereotactic body radiotherapy
Subjects
Details
- ISSN :
- 12783218
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Cancer/Radiothérapie
- Accession number :
- edsair.doi...........26d4e043f42d2900bf93f65744a6a2d4