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Annomontacine: Une Nouvelle Acétogénine γ-Lactone-monotetrahydrofurannique Cytotoxique de l'Annona montana
- Source :
- Journal of Natural Products. 54:967-971
- Publication Year :
- 1991
- Publisher :
- American Chemical Society (ACS), 1991.
-
Abstract
- The structure of annomontacin [I], a novel monotetrayhydrofuran fatty acid gamma-lactone (acetogenin) isolated from the seeds of Amnona montana, was determined by spectral analysis. The cytotoxicities in vitro of annomontacin [I], annonacinone [2], and annonacin were measured against murine leukemia L1210, human breast adenocarcinoma MDA-MB231, and human breast carcinoma MCF7 cell lines and compared with adriamycin.
- Subjects :
- Pharmacology
chemistry.chemical_classification
biology
Organic Chemistry
Annonacin
Pharmaceutical Science
Fatty acid
Pharmacognosy
medicine.disease
biology.organism_classification
Molecular biology
Annona montana
In vitro
Analytical Chemistry
chemistry.chemical_compound
Complementary and alternative medicine
chemistry
Annonaceae
Drug Discovery
Acetogenin
medicine
Molecular Medicine
Adenocarcinoma
skin and connective tissue diseases
Subjects
Details
- ISSN :
- 15206025 and 01633864
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Journal of Natural Products
- Accession number :
- edsair.doi...........26d00725263ae9a78db382e633168e7d
- Full Text :
- https://doi.org/10.1021/np50076a007