Generation and Intramolecular Cycloaddition ofo-Quinonemethides in Protic Solvent. An Efficient Synthesis of (−)-trans-Hexahydrocannabinol

Authors :: Zhan Guo Lu
Noriaki K. Sato
Kikumasa Sato
Seiichi Inoue
Source :: Chemistry Letters. 21:1237-1238
Publication Year :: 1992
Publisher :: The Chemical Society of Japan, 1992.
Abstract: A very facile and efficient synthesis of (−)-trans-hexahydrocannabinol was achieved through the intramolecular Diels-Alder reaction of an o-quinonemethide derived from 2-(1-hydroxycitronellyl)olivetol 1,3-bismethoxymethyl ether in methanol.

Subjects :: chemistry.chemical_compound
chemistry
Intramolecular reaction
Intramolecular force
Ether
General Chemistry
Methanol
Olivetol
Aliphatic compound
Medicinal chemistry
Cycloaddition
Protic solvent

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