NIR-excited upconversion nanoparticles used for targeted inhibition of Aβ42 monomers and disassembly of Aβ42 fibrils

Authors :: Yijia Guan
Weijie Cao
Tao Li
Jieyi Qin
Qilong He
Xiaofeng Jia
Yuqing Li
Yuhua Zhang
Jianguo Liao
Source :: Journal of Materials Chemistry B. 11:1445-1455
Publication Year :: 2023
Publisher :: Royal Society of Chemistry (RSC), 2023.
Abstract: Herein, we designed and constructed functional upconversion nanoparticles (UCNPs@SiO2-ThS), which can not only inhibit the aggregation of Aβ42 monomers, but also disassemble Aβ42 fibrils under the irradiation of near-infrared (NIR) light.

Subjects :: Biomedical Engineering
General Materials Science
General Chemistry
General Medicine

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