Selectivity of Benzodioxane α-Adrenoceptor Antagonists for α1-and α2-Adrenoceptors Determined by Binding Affinity

Authors :: J. E. Van Kemenade
P. A. Van Zwieten
H. D. Batink
Pieter B.M.W.M. Timmermans
Source :: Pharmacology. 26:258-269
Publication Year :: 1983
Publisher :: S. Karger AG, 1983.
Abstract: A series of benzodioxane derivatives, structurally related to WB 4101 and piper-oxan as well as prazosin and its two analogues UK-18,596 and UK-33,274, was studied with respect to their affinity for α

Subjects :: Pharmacology
α2 adrenoceptor
Biochemistry
Stereochemistry
Chemistry
Prazosin
medicine
General Medicine
α adrenoceptors
Selectivity
medicine.drug

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