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Immune Cell-Supplemented Human Skin Model for Studying Fungal Infections
- Source :
- Methods in Molecular Biology ISBN: 9781493965137
- Publication Year :
- 2016
- Publisher :
- Springer New York, 2016.
-
Abstract
- Human skin is a niche for various fungal species which either colonize the surface of this tissue as commensals or, primarily under conditions of immunosuppression, invade the skin and cause infection. Here we present a method for generation of a human in vitro skin model supplemented with immune cells of choice. This model represents a complex yet amenable tool to study molecular mechanisms of host-fungi interactions at human skin.
- Subjects :
- 0301 basic medicine
integumentary system
biology
medicine.medical_treatment
030106 microbiology
Cell
Immunosuppression
Human skin
biology.organism_classification
Jurkat cells
In vitro
03 medical and health sciences
030104 developmental biology
medicine.anatomical_structure
Immune system
Cell culture
Immunology
medicine
Candida albicans
Subjects
Details
- ISBN :
- 978-1-4939-6513-7
- ISBNs :
- 9781493965137
- Database :
- OpenAIRE
- Journal :
- Methods in Molecular Biology ISBN: 9781493965137
- Accession number :
- edsair.doi...........24ed49c934723d0e1f8cbadf0cc2e956
- Full Text :
- https://doi.org/10.1007/978-1-4939-6515-1_25