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Immune Cell-Supplemented Human Skin Model for Studying Fungal Infections

Authors :
Anke Burger-Kentischer
Andreas Kühbacher
Steffen Rupp
Kai Sohn
Source :
Methods in Molecular Biology ISBN: 9781493965137
Publication Year :
2016
Publisher :
Springer New York, 2016.

Abstract

Human skin is a niche for various fungal species which either colonize the surface of this tissue as commensals or, primarily under conditions of immunosuppression, invade the skin and cause infection. Here we present a method for generation of a human in vitro skin model supplemented with immune cells of choice. This model represents a complex yet amenable tool to study molecular mechanisms of host-fungi interactions at human skin.

Details

ISBN :
978-1-4939-6513-7
ISBNs :
9781493965137
Database :
OpenAIRE
Journal :
Methods in Molecular Biology ISBN: 9781493965137
Accession number :
edsair.doi...........24ed49c934723d0e1f8cbadf0cc2e956
Full Text :
https://doi.org/10.1007/978-1-4939-6515-1_25