The Effects of Urinary Gonadotropins Following Hypophysectomy and in Hypogonadotropic Eunuchoidism

I should like to present summaries of two new cases treated with gonadotropins. The first is that of a 28-year-old married man with two children who had undergone hypophysectomy for an infarcted adenoma of the pituitary. I saw him for the first time one and a half years after this operation. He had returned to the neuro-sur-geon (Dr. Bronson Ray) because his wife desired another child. In the interim, he had been supported only by cortisone and thyroid. He had not received androgens. He complained of low libido, loss of ejaculate and of pubic, axillary and body hair. He could attain erections and orgasm after considerable stimulation. He had not experienced a spontaneous erection since the operation. It was ascertained that he had been under-active sexually during his married life and before the illness that precipitated the operation. The post-operative loss of libido therefore, had not bothered him unduly. He could not produce an ejaculate for examination in spite of erection and orgasm.