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Potential Test of Soy-yamghurt against Antidiabetic in male white rats (Rattus norvegicus) Streptozotocin induced

Authors :
Tien Wahyu Handayani
Viani Anggi
Afrizal Afrizal
Magfirah Magfirah
Joni tandi
Source :
Research Journal of Pharmacy and Technology. :4139-4143
Publication Year :
2022
Publisher :
A and V Publications, 2022.

Abstract

Background: Soy-yamghurt is a fermented product of soy and sweet potato juice made from the addition of lactic acid bacteria and is thought to have antioxidant abilities, function to repair pancreatic cells, and reduce blood glucose levels. Aim: This study aims to determine the potential of soy-yamghurt probiotic drinks to decrease blood glucose levels of male white rats (Rattus novergicus). Method: This study used 30 rats divided into six treatment groups, namely normal control (NaCMC), negative control (streptozotocin+NA CMC), positive control (streptozotocin+glibenclamide), treatment formula 1 (streptozotocin+sweet potato juice+ soybean juice (1:1), formula 2(streptozotocin+sweet potato juice+soybean juice (1:2)), and formula 3(streptozotocin+sweet potato juice+soybean juice (2:1)). Results: The results showed that the average blood glucose levels were normal control (100.4mg/dL), negative control (298.8mg/dL), positive control (81.2mg/dL), formula 1(178.4mg/dL), formula 2(108.0mg). /dL), formula 3(134.4mg/dL). Conclusion: soy-yamghurt affects reducing blood glucose levels with an effective formula, namely formula 2 by giving 3.4ml.

Details

ISSN :
0974360X and 09743618
Database :
OpenAIRE
Journal :
Research Journal of Pharmacy and Technology
Accession number :
edsair.doi...........23bf462ee6b54427071721e7a65c2574
Full Text :
https://doi.org/10.52711/0974-360x.2022.00695