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Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent

Authors :
Yu-I Weng
I-Lu Lai
Ching-Shih Chen
Dau-Ming Niu
Yi-Chiu Kuo
Tim H M Huang
Shuan-Pei Lin
Hsiang-Yu Lin
Source :
The Prostate. 72:1767-1778
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

BACKGROUND Targeting tumor metabolism by energy restriction-mimetic agents (ERMAs) has emerged as a strategy for cancer therapy/prevention. Evidence suggests a mechanistic link between ERMA-mediated antitumor effects and epigenetic gene regulation.

Details

ISSN :
02704137
Volume :
72
Database :
OpenAIRE
Journal :
The Prostate
Accession number :
edsair.doi...........237571ac942aafe7dc6ff2317a0c3496
Full Text :
https://doi.org/10.1002/pros.22530