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Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data
- Source :
- Clinical Infectious Diseases. 74:1260-1264
- Publication Year :
- 2021
- Publisher :
- Oxford University Press (OUP), 2021.
-
Abstract
- This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.
- Subjects :
- Microbiology (medical)
Mechanical ventilation
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
business.industry
medicine.medical_treatment
Infectious Diseases
Risk groups
Treatment trial
Oxygen breathing
Emergency medicine
Cohort
Post-hoc analysis
medicine
Treatment effect
business
Subjects
Details
- ISSN :
- 15376591 and 10584838
- Volume :
- 74
- Database :
- OpenAIRE
- Journal :
- Clinical Infectious Diseases
- Accession number :
- edsair.doi...........230b61c921454b0c03a80539a1f29583