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Keep trying or give up? the future fertility of patients undertaking their first in vitro fertilization with no available embryos
- Publication Year :
- 2022
- Publisher :
- Research Square Platform LLC, 2022.
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Abstract
- In in vitro fertilization (IVF), the patient's probability of subsequent pregnancy after a failed procedure with no transferable embryo is unknown. We conducted a cohort retrospective study evaluating the live birth rate in the subsequent cycles of the patients with no embryo transfer in their first IVF attempt between 2017and 2020. The variables in the first cycle were compared between the patients who conceived in subsequent cycles and who did not. Additionally, for patients who conceived at last, variables related to ovarian stimulation were compared between the first cycle and the pregnancy cycle. According to the inclusion criteria, 529 were enrolled during the study period, of which 230 had successful pregnancies and 192 gave birth to a live infant. Cumulative live birth rates (CPR) per cycle and per patient were 26%, 36% respectively. 99% of the live births were obtained within the first 3 attempts, no pregnancy was achieved beyond 6 cycles. Stimulating variables in the first cycle were not effective in predicting the likelihood of a patient's subsequent pregnancy. Overall, patients who did not have embryos available for transfer in the first cycle had a 36% chance of having a live birth in subsequent attempts, and more than three attempts were not recommended.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi...........22e719bb31ee98d89153db3a428274ca