Capillary Thrombosis as a Factor in the Evolution of Traumatic Brain Lacerations

In a group of patients with Traumatic Brain Laceration (TBL) studies on blood coagulation and platelet function were performed in blood samples obtained during angiography from the omolateral carotid artery and jugular vein. Intraoperatory microbiopsies were also performed during neurosurgical operations in patients with TBL at different stages of evolution. In the acute stages of TBL necrosis of the endothelium and extensive micro-thrombosis with platelet material occurs in the capillaries around the damaged area. In the blood obtained from the jugular vein a fall in platelet count, platelet materials and positive paracoagulation tests can be observed.These data suggest that a process of regional intravascular coagulation occurs after TBL around the damaged area. Resulting microthrombosis may be regarded as a significant factor in the pathogenesis of acute ischemic intracellular edema in neurotraumatology.