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Sodium hypophosphite mediated reductive amination of carbonyl compounds with N,N-dialkylformamides

Authors :
Artemy R. Fatkulin
Vasily Korochantsev
Oleg I. Afanasyev
Evgeniya Podyacheva
Olga Chusova
Dmitry V. Muratov
Maria I. Godovikova
Sergei Semenov
Denis Chusov
Source :
New Journal of Chemistry. 47:6532-6535
Publication Year :
2023
Publisher :
Royal Society of Chemistry (RSC), 2023.

Abstract

Herein we report a transition-metal- and acid-free protocol for the reductive amination of carbonyl compounds with DMF using a substoichiometric amount of NaH2PO2·H2O. The general trends and limitations of the method were explored.

Details

ISSN :
13699261 and 11440546
Volume :
47
Database :
OpenAIRE
Journal :
New Journal of Chemistry
Accession number :
edsair.doi...........2224426d8cb3cabcf9779f54f0719def
Full Text :
https://doi.org/10.1039/d3nj00728f