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Radiation Effects on Cold-Induced Growth Response of Interscapular Brown Fat
- Source :
- Radiation Research. 38:55
- Publication Year :
- 1969
- Publisher :
- JSTOR, 1969.
-
Abstract
- When rats are transferred to a 5°C environment immediately after exposure to 400 R of x-irradiation, the rate of growth of interscapular brown fat is significantly inhibited, in comparison with that in pair-fed unirradiated cold-exposed controls. The most striking effect is on the early hyperplasia of the tissue, which in the controls is maximal after 3 days in the cold. After 3 weeks, the mass of interscapular brown fat in the irradiated animals is only slightly less than that in control rats, but the total amounts of various components of the tissue (total nitrogen, nucleic acids, phospholipids, respiratory enzymes) remain below the control level for at least 5 weeks. It seems unlikely that decreased thermogenic activity is of major importance in reducing the survival of cold-exposed irradiated rats.
- Subjects :
- medicine.medical_specialty
Control level
Radiation
biology
Chemistry
Succinate dehydrogenase
Biophysics
Adipose tissue
Hyperplasia
medicine.disease
Endocrinology
Internal medicine
medicine
Total nitrogen
biology.protein
Radiology, Nuclear Medicine and imaging
Respiratory enzymes
Radiosensitivity
Rate of growth
Subjects
Details
- ISSN :
- 00337587
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Radiation Research
- Accession number :
- edsair.doi...........21d6074665414468214e3670ecc6da01
- Full Text :
- https://doi.org/10.2307/3572710