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An add-on adaptive optical module for laser scanning microscopy (Conference Presentation)
- Source :
- Adaptive Optics and Wavefront Control for Biological Systems IV.
- Publication Year :
- 2018
- Publisher :
- SPIE, 2018.
-
Abstract
- Wavefront-shaping devices incorporated into optical microscopy systems are capable of correcting sample-induced aberrations and recovering diffraction-limited imaging performance. The widespread dissemination and application of adaptive optical techniques, however, requires easy integration of adaptive optical modules, both in terms of hardware and software, into existing microscopes. We built an adaptive optical module with reduced complexity and simplified integration by utilizing a novel segmented deformable mirror and a standalone control software program. We demonstrated its ability to improve image brightness and resolution at depth in the mouse, zebrafish, and fly brains in vivo.
- Subjects :
- Brightness
Laser Scanning Microscopy
Microscope
genetic structures
business.industry
Computer science
ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION
eye diseases
Deformable mirror
law.invention
Optical Module
Software
Optical microscope
law
sense organs
business
Adaptive optics
Computer hardware
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Adaptive Optics and Wavefront Control for Biological Systems IV
- Accession number :
- edsair.doi...........21d2551dd408e434b82089a12953109f
- Full Text :
- https://doi.org/10.1117/12.2292944