Antimicrobial effect of monomers and polymers with azole moieties

Five monomers with azole moieties were synthesized and their antimicrobial activities were investi- gated. The antimicrobial activity of the monomers was eval- uated by the halo zone test method. The results strongly depended on the chemical structure of the group attached to the azole moieties. Polymers with (benzimidazol-2-yl)thio groups and with (5-methyl-1,3,4-thiadiazol-2-yl)thio groups were synthesized. The shake flask test showed that the two polymers possessed excellent antimicrobial activity. © 2003