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1619 ANDROGRAPHOLIDE IS A NOVEL INHIBITOR OF INTERLEUKIN-6 AND SUPPRESSES PROSTATE TUMOR GROWTH
- Source :
- Journal of Urology. 185
- Publication Year :
- 2011
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2011.
-
Abstract
- Olympus BX61WI upright frame and a modified Bio-Rad MRC 1024 scanhead was used. The corresponding tissues were subjected to hematoxylin and eosin staining for histologic confirmation of the structures. RESULTS: High-resolution images of the periprostatic tissue, nerves, prostate capsule, underlying acini, and individual acinar cells were obtained at varying magnifications (Figure). Histologic confirmation and correlation of the periprostatic tissue, prostate gland, fat, blood vessels, and nerves validated the findings of MPM. CONCLUSIONS: We have utilized a novel approach for tissue imaging which appears to provide microscopy level resolution in fresh tissue, without the need for any extrinsic labeling agents. This may allow for more accurate surgical decision making during nerve sparing radical prostatectomy and will also improve the accuracy of prostate biopsy when used to guide tissue sampling, once the technology is clinically translated.
- Subjects :
- Pathology
medicine.medical_specialty
Prostate biopsy
biology
medicine.diagnostic_test
business.industry
Urology
Andrographolide
H&E stain
chemistry.chemical_compound
medicine.anatomical_structure
chemistry
Fresh Tissue
Prostate
Prostate Capsule
biology.protein
medicine
Tumor growth
Interleukin 6
business
Subjects
Details
- ISSN :
- 15273792 and 00225347
- Volume :
- 185
- Database :
- OpenAIRE
- Journal :
- Journal of Urology
- Accession number :
- edsair.doi...........218635bc372aed90cde9fb20c35e8843
- Full Text :
- https://doi.org/10.1016/j.juro.2011.02.1727