Back to Search
Start Over
Single Positive Commensal Blood Culture in hospital setting is associated with higher mortality after hematopoietic stem cell transplantation
- Source :
- Acta Haematologica Polonica. 48:40-47
- Publication Year :
- 2017
- Publisher :
- Walter de Gruyter GmbH, 2017.
-
Abstract
- Background Single positive staphylococcal blood culture in a hematopoietic stem cell transplantation (HSCT) recipient is generally regarded as contamination. Such a blood culture (BC) does not fill the criteria for Laboratory-Confirmed Bloodstream Infection (LCBI) and could be described as Single Positive Commensal Blood Culture. The aim of this retrospective cohort analysis was to determine the clinical significance of SPCBC in HSCT recipients. Methods 206 patients transplanted between 2007 and 2013 were followed until January 2015. Results The 100-day survival for patients without positive BC was 99.6% compared with 83.9% for LCBI and 82.8% for SPCBC (p = 0.0036). The 5-year overall survival (5yOS) was 67.1% for patients without positive BC, 44.9% for LCBI, 34.0% for SPCBC (p Conclusion To our knowledge this is the first report that specifically shows that short- and long-term survival after HSCT is significantly lower in patients who experience an episode of SPCBC with Staphylococcus spp. during HSCT hospitalization.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
biology
medicine.diagnostic_test
Hospital setting
business.industry
medicine.medical_treatment
030106 microbiology
Retrospective cohort study
Hematology
Hematopoietic stem cell transplantation
medicine.disease
biology.organism_classification
medicine.disease_cause
Sepsis
03 medical and health sciences
Oncology
Staphylococcus epidermidis
Internal medicine
Immunology
medicine
Clinical significance
Blood culture
business
Staphylococcus
Subjects
Details
- ISSN :
- 00015814
- Volume :
- 48
- Database :
- OpenAIRE
- Journal :
- Acta Haematologica Polonica
- Accession number :
- edsair.doi...........217c17bdb5a4bb09fc29414910d67468