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Fragments d’anticorps à domaine unique
- Source :
- médecine/sciences. 25:1159-1162
- Publication Year :
- 2009
- Publisher :
- EDP Sciences, 2009.
-
Abstract
- Monoclonal antibodies are now established as key therapeutics for a range of diseases including cancer and auto-immunity. However, despite important improvements, these molecules still face several serious limitations including production costs and tumor penetration. A new class of antibody fragments, made of a single immunoglobulin domain, is emerging as an exciting alternative. This review describes the outstanding properties and the first achievements of these domain antibodies.
- Subjects :
- Anticorps monoclonal
medicine.drug_class
Tumor penetration
General Medicine
Computational biology
Immunoglobulin domain
Biology
Monoclonal antibody
General Biochemistry, Genetics and Molecular Biology
Antibody fragments
Domain (software engineering)
Still face
medicine
biology.protein
Antibody
Subjects
Details
- ISSN :
- 19585381 and 07670974
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- médecine/sciences
- Accession number :
- edsair.doi...........20973219a65c9176db80bdb5926c6068