ACUPUNCTURE AND MORPHINE ANALGESIA INHIBITORY SYSTEMS AND ITS CORRELATION WITH MORPHINE TOLERANCE

Two acupuncture analgesia (AA) afferent pathways were identified by lesion of the lateral centromedian nucleus of thalamus(1-CM). One is, and the other is not inhibited by 1-CM during AA, 0.5 mg/kg morphine analgesia(MA) or dorsal periaqueduct central gray stimulation-produced analgesia(d-PAG-SPA). Morphine tolerance might develop in the analgesia inhibitory system.