ChemInform Abstract: A Novel Synthesis of 19-Nor-1α,25-dihydroxyvitamin D3 and Related Analogues

19-Nor-1 α,25-dihydroxyvitamin D 3 ( 2 ) was synthesized from A-ring precursor 5 and ketone 4 . Two synthesis of 5 were studied; one starting from (-)-quinic acid as a template and one starting from cis-1,3,5-cyclohexanetriol via a chemoenzymatic approach.