ChemInform Abstract: A FeCl3-Catalyzed Highly Regioselective 1,2-Addition/Substitution Sequence for the Construction of Coumarin-Substituted Bis(indolyl)methanes

Authors :: Qi-Lin Wang
Yan-Shuo Zhu
Wen-Bo Wang
Sheng-Qiang Guo
Zhanwei Bu
Source :: ChemInform. 47
Publication Year :: 2016
Publisher :: Wiley, 2016.
Abstract: A FeCl3-catalyzed highly regioselective 1,2-addition/substitution sequence of 3-acetylcoumarins and indoles has been developed to afford highly hindered tetrasubstituted bis(indolyl)methanes bearing a biologically useful coumarin motif in 56–99% yields.

Subjects :: chemistry.chemical_compound
chemistry
Stereochemistry
Substitution (logic)
Regioselectivity
General Medicine
Coumarin
Catalysis
Sequence (medicine)

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