Back to Search
Start Over
Enantioselective Synthesis of Coumarins Catalyzed by Chiral Squaramide
Enantioselective Synthesis of Coumarins Catalyzed by Chiral Squaramide
- Source :
- Letters in Organic Chemistry. 19:919-923
- Publication Year :
- 2022
- Publisher :
- Bentham Science Publishers Ltd., 2022.
-
Abstract
- Abstract: A newly chiral tertiary amine-squaramide has successfully developed and applied into the asymmetric Michael addition of 4-hydroxycoumarin to β,γ-unsaturated α-ketoesters. The catalyst system performed well with a low catalyst loading of 1 mol% under mild reaction conditions. A series of coumarin derivatives were obtained with good yields and enantioselectivities.
- Subjects :
- Organic Chemistry
Biochemistry
Subjects
Details
- ISSN :
- 15701786
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Letters in Organic Chemistry
- Accession number :
- edsair.doi...........1f9710d67d67505d476ae62af4616a33
- Full Text :
- https://doi.org/10.2174/1570178619666220309155353