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The role of Pectin in controlling the changes induced by Mercuric Chloride in albino rats fetuses

Authors :
Haifaa Al Fassam
H Abu Gabal
Source :
The Egyptian Journal of Hospital Medicine. 47:145-157
Publication Year :
2012
Publisher :
Egypts Presidential Specialized Council for Education and Scientific Research, 2012.

Abstract

The present work was planned to investigate the role of Pectin in ameliorating the morphometric, morphological and skeletal changes induced by mercury in albino rat's fetuses. 50 Wistar wistar virgin female rats were used in the present study and 25 males for mating. The results of the present work showed that the exposure of the pregnant rats to mercury chloride at a dose 5mg/kg body weight lead to significant decrease in fetal body weights as well as body and tail lengths. Also, mercury chloride administration of the pregnant rats resulted in some changes in experimental morphology of the fetuses. In addition, the fetal skeletal system was affected as follows; increase of the number of non ossified bones in the axial and peripheral systems. Pectin treatment of the pregnant rats improved the fetuses’ morphometric, morphological and skeletal changes.

Details

ISSN :
20907125
Volume :
47
Database :
OpenAIRE
Journal :
The Egyptian Journal of Hospital Medicine
Accession number :
edsair.doi...........1ef77c4ff2e8269d20d3aa21ff00e28a
Full Text :
https://doi.org/10.21608/ejhm.2012.16288