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Development of treatment and clinical results in childhood acute myeloid leukemia in the Slovak Republic

Authors :
Martina Mikesková
Emilia Kaiserova
Sabina Sufliarska
Eva Bubanska
Zuzana Laluhova Striezencova
Stanislava Hederová
Daniela Sejnova
Alexandra Kolenova
Lucia Copakova
Anna Foltinova
Dana Petrzalkova
Irina Oravkinova
Oksana Fabri
Júlia Horáková
Alica Chocholova
Jan Cap
Zuzana Subova
Source :
memo - Magazine of European Medical Oncology. 6:46-53
Publication Year :
2012
Publisher :
Springer Science and Business Media LLC, 2012.

Abstract

Background Acute myeloid leukemia (AML) in children is rare, and it is generally considered to be more resistant to chemotherapy than acute lymphoblastic leukemia. However, because of the gradual intensification of chemotherapy and better supportive care, outcomes have improved considerably over the past 20 years. The management of children with AML in the Slovak Republic was unified and centralized during the second half of the 1990s with the introduction of Berlin-Frankfurt-Munster (BFM) protocols. In 2000, the AML-BFM-1998 protocol was introduced, and data collection became centralized.

Details

ISSN :
18655076 and 18655041
Volume :
6
Database :
OpenAIRE
Journal :
memo - Magazine of European Medical Oncology
Accession number :
edsair.doi...........1edd1f44350be902d9e9056ab2a82b4c