Additional file 1 of Association of lysophosphatidic acids with cerebrospinal fluid biomarkers and progression to Alzheimer’s disease

Additional file 1: Table S1. List of detected lysophosphatidic acids in cerebrospinal fluid and plasma. Table S2. Association of metabolites in plasma association with amyloid-beta 42, P-Tau and total tau. Table S3. Association of metabolites in cerebrospinal fluid with APOE 22/23 versus APOE 33. Table S4. Association of metabolites in cerebrospinal fluid with APOE 44/34/24 vs APOE 33. Table S5. Association of metabolites measured in CSF with MCI to AD conversion in ACE cohort. Table S6. Association of metabolites measured in CSF with MCI to AD conversion adjusting for APOE in ACE cohort. Table S7. Association of metabolites measured in CSF with MCI to AD conversion adjusted for amyloid beta 42 levels in ACE cohort. Table S8. Association of metabolites measured in plasma with MCI to AD conversion in ACE cohort. Table S9. Association of metabolites measured in CSF with MCI to AD conversion in Heidelberg/Mannheim sample. Table S10. Association of the Mini-Mental State Examination (MMSE) with LPAs in CSF. Table S11. Association of the clinical dementia score (CDR) with LPAs in CSF. Figure S1. Correlation of metabolite levels between plasma and CSF. Figure S2. Correlation matrix of CSF LPA metabolites.