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Survival rates in HLA-A2 positive patients, with stage III-IV serous adenocarcinomas of the ovary, correlates with increased expression of COX-2 and iNOS, loss of MHC Class I and II and defects of the antigen processing mechanisms at the tumour level

Authors :
Hildur Helgadottir
Barbara Seliger
C. C. Johansson
Rolf Kiessling
Kjell Bergfeldt
Tina Dalianis
Emilia Andersson
Soldano Ferrone
Giuseppe Masucci
L. Kanter
Lisa Villabona
Source :
Journal of Clinical Oncology. 26:16544-16544
Publication Year :
2008
Publisher :
American Society of Clinical Oncology (ASCO), 2008.

Abstract

16544 Background: We have shown that the high prevalence of HLA-A2 in Scandinavia is associated to poor prognosis in advanced (stage III-IV) serous adenocarcinoma of the ovary. Our objective was to...

Details

ISSN :
15277755 and 0732183X
Volume :
26
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........1e79585d38d0fa7e350bab1bbbd1d148
Full Text :
https://doi.org/10.1200/jco.2008.26.15_suppl.16544