OROPHARYNGEAL MICROBIOTA IN CHILDREN WITH WEB INFECTION ON THE BACKGROUND OF ANTIBIOTIC THERAPY

According to statistics from the World Health Organization, infectious mononucleosis caused by Epstein-Barr virus affects 90% of the world's population. The aim of this study was to study the composition of the oropharyngeal microbiota and to determine the antibiotic sensitivity of its representatives, which are released in clinically significant concentrations from children with WEB infection who received antibiotic therapy. 28 patients with WEB infection in children aged 5 to 16 years were examined. Among the 28 children in inpatient treatment, 78.6% were patients under the age of 10. All children received antibiotic therapy, although according to treatment protocols, it is indicated only in the case of a bacterial infection. Streptococcus spp. with β-hemolysis (64.3%). Detection of S. aureus in 35.7% of patients indicates a violation of the structure of the normal microbiocenosis of the oropharynx. The study of antibiotic susceptibility of staphylococci and streptococci showed the presence of resistance in 52.6% of isolated strains of streptococci and 25.0% of staphylococci to azithromycin.