ChemInform Abstract: Synthesis and Pharmacological Study of a Series of 3(2H)-Pyridazinones as Analgesic and Antiinflammatory Agents

The synthesis and the pharmacological evaluation of some 3(2H)-pyridazinone derivatives are reported. The compounds were screened for analgesic, antiinflammatory and antipyretic activities. All tested derivatives showed a higher analgesic activity than phenylbutazone, while being devoid of ulcerogenic action.