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Meta-cognitive q-Gaussian RBF network for binary classification: Application to mild cognitive impairment (MCI)
- Source :
- IJCNN
- Publication Year :
- 2013
- Publisher :
- IEEE, 2013.
-
Abstract
- In this paper, we present a novel approach for classification of Mild Cognitive Impairment (MCI) and normal subjects from Magnetic Resonance Images (MRI) using a proposed `sequential Projection Based Learning for Meta-cognitive q-Gaussian Radial Basis Function Network (PBL-McqRBFN)' classifier. The McqRBFN has two components, namely, a cognitive component and a meta-cognitive components. The cognitive component is a single hidden layer Radial Basis Function (RBF) network with a q-Gaussian activation function, that allows different RBF's in one network, like the Gaussian, the Inverse Multiquadratic, and the Cauchy functions, by changing a real q-parameter. The meta-cognitive component present in McqRBFN helps in selecting proper samples to learn based on its current knowledge and evolve architecture automatically. The McqRBFN employs a sequential Projection Based Learning (PBL) algorithm to reduce the computational effort used in training. For simulation studies, we have used MRI data from the Alzheimer's Disease Neuroimaging Initiative database. Voxel Based Morphometry (VBM) is used for feature extraction from MRI data and extracted VBM features are fed into the PBL-McqRBFN classifier. The experimental results show that our proposed PBL-McqRBFN classifier can accurately differentiate MCI and normal subjects.
- Subjects :
- Radial basis function network
Computer science
business.industry
Gaussian
Feature extraction
Activation function
Pattern recognition
Machine learning
computer.software_genre
medicine.disease
symbols.namesake
Binary classification
symbols
medicine
Radial basis function
Artificial intelligence
Mild cognitive impairment (MCI)
Cognitive impairment
business
Gaussian process
Classifier (UML)
computer
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- The 2013 International Joint Conference on Neural Networks (IJCNN)
- Accession number :
- edsair.doi...........1ccb505ee6d51db6019d26190aa5aa64