Fatal Ecstasy-induced malignant hyperthermia with rhabdomyolysis. A case report

There is an increasing number of reports concerning lethal courses following consumption of 3,4-Methylenedioxymethamphetamine (MDMA), namely Ecstasy. Autopsy findings in cases of MDMA intoxications are described, however Ecstasy-associated pathological findings should be separated from Ecstasy-induced findings. This case report presents typical Ecstasy-induced findings due to an obviously genetic disposition leading to malignant hyperthermia and severe rhabdomyolysis. Medicolegal aspects are relevant because there is a therapeutic option to save life by injecting Dantrolene when first symptoms are recognized.