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Solubility of salbutamol and salbutamol sulphate in ethanol+water mixtures at 25°C
- Source :
- Journal of Molecular Liquids. 173:62-65
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- Experimental solubilities of salbutamol and salbutamol sulphate in ethanol + water mixtures at 25 °C are reported. The solubility of salbutamol was found to increase with the addition of ethanol, and reached a maximum value at an ethanol volume fraction of 0.8. The solubility of salbutamol sulphate decreased with increasing ethanol concentration, and reached a minimum value in ethanol. The Jouyban-Acree model correlated the measured salbutamol and salbutamol sulphate solubility data to within mean relative deviations (MRD) of 3.4 and 13.4, respectively. Solubilities were predicted using previously trained models developed for crystalline non-electrolyte and electrolyte solutes. The trained models for non-electrolytes and electrolytes produced the prediction MRDs of 22.4 and 19.8, respectively. Crown Copyright © 2012 Published by Elsevier B.V. All rights reserved.
- Subjects :
- Chromatography
Ethanol
Electrolyte
Salbutamol Sulphate
Condensed Matter Physics
Atomic and Molecular Physics, and Optics
respiratory tract diseases
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
chemistry
Volume fraction
Materials Chemistry
Salbutamol
medicine
Physical and Theoretical Chemistry
Solubility
Spectroscopy
medicine.drug
Subjects
Details
- ISSN :
- 01677322
- Volume :
- 173
- Database :
- OpenAIRE
- Journal :
- Journal of Molecular Liquids
- Accession number :
- edsair.doi...........1c19a9ecd37b244b42be4b4a0c1f3b7e