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Modelisation, synthesis and antiviral evaluation of new 2,3-disubstituted thiazolidinone nucleoside analogues
- Source :
- Bioorganic & Medicinal Chemistry Letters. 6:1775-1780
- Publication Year :
- 1996
- Publisher :
- Elsevier BV, 1996.
-
Abstract
- The syntheses, anti-HIV and anti-HBV in vitro evaluations of new thiazolidinone nucleoside analogues are described. Preliminary molecular modeling studies demonstrated that these new analogues conserved the essential elements of the hypothesized biological active synthon.
Details
- ISSN :
- 0960894X
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Accession number :
- edsair.doi...........1a845ef2dd6cd5c350e5250fb0a9e48c
- Full Text :
- https://doi.org/10.1016/0960-894x(96)00316-2