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4‐Phenylbutyrate rescues folding‐deficient creatine transporter‐1 variants linked to the creatine transporter deficiency syndrome

Authors :
Sonja Sucic
Ali El-Kasaby
Michael Freissmuth
Source :
The FASEB Journal. 33
Publication Year :
2019
Publisher :
Wiley, 2019.

Abstract

Mutations in the coding sequence of the hCRT-1 gene (SLC6A8) have been associated with the creatine transporter deficiency (CTD) syndrome. CTD encompasses a range of moderate to severe conditions, ...

Details

ISSN :
15306860 and 08926638
Volume :
33
Database :
OpenAIRE
Journal :
The FASEB Journal
Accession number :
edsair.doi...........1a27469001a945c55a87599109c3f1ed
Full Text :
https://doi.org/10.1096/fasebj.2019.33.1_supplement.780.12