Exploring the Frontiers of Serotoninomics in Male Reproduction: The Future Ahead

Since its discovery in the past century by Green, Page and Rapport (1948), to the present time, several physiological actions of serotonin has been discovered. Besides physiological functions, several components of serotoninergic system and its participation in some neurological diseases (i.e. depression, schizophrenia) also have been reported. During previous decades, a lot of experimental techniques have allowed us to locate, detect, analyze and describe the serotoninergic system and its role in different organs and tissues; at the time of 60’s and 70’s of century XX, techniques such as histochemistry for indolamines or Falck-Hillarp method, fluorescence microscopy and the realization of measurements of concentrations in tissues or blood using chromatography enabled significant progress in the study of this indolamine