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ChemInform Abstract: A Practical Asymmetric Synthesis of Homochiral α-Arylglycines

Authors :
David J. Aitken
Christelle Mellin-Morlière
Steven D. Bull
Stephen G. Davies
Henri-Philippe Husson
Source :
ChemInform. 32
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral α-arylglycines in high e.e.

Details

ISSN :
15222667 and 09317597
Volume :
32
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........172706383c060ece7d64fafd549db4e4
Full Text :
https://doi.org/10.1002/chin.200131190