Antifungal activity of natural compounds against thiabendazole-resistant Fusarium sambucinum strains

Several natural compounds that had been previously identified as effective potato sprout inhibitors were examined for antifungal activity against three thiabendazole (TBZ)-resistant strains and a TBZ-sensitive (wild-type) strain of Fusarium sambucinum. Salicylaldehyde was the most inhibitory compound of those tested when applied as a volatile and completely inhibited fungal growth at headspace gas levels of 20 μg/mL or lower. Cinnamaldehyde, salicylaldehyde, and thymol prevented all growth when incorporated in media at 0.1% (v/v) levels. TBZ-resistant strains were only partially inhibited by TBZ concentrations that completely inhibited the wild-type strain