Novel small-molecule inhibitors of ecto-nucleotidase CD73: Activation of human CD8+ T cells and effects on tumor growth and immune parameters in experimental tumor models

Authors :: Ulrike Schindler
Steve Young
Jay P. Powers
J. Jaen
E. Sharif
J. Tan
H. Sexton
D. Miles
T. Park
A. Chen
Manmohan Reddy Leleti
Source :: European Journal of Cancer. 69:S96
Publication Year :: 2016
Publisher :: Elsevier BV, 2016.

Subjects :: Cancer Research
Immune system
Oncology
Chemistry
Immunology
Cancer research
Cytotoxic T cell
Tumor growth
Ecto nucleotidases
Small molecule

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