Regulation of Sulphur Metabolism in Paracoccus denitrificans

The metabolic pathway for the reduction and incorporation of sulphate in Paracoccus denitrificans strain NCIB 8944 has been elucidated and the control and regulation of the pathway is reported. Several enzymes of the sulphate metabolic pathway have been assayed in P. denitrificans grown on different substrates. In addition, several enzymes have been purified and in vitro inhibitor studies conducted on them. Cysteine plays a primary role in the control of sulphur metabolism in P. denitrificans.