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Antimicrobial Therapy and Late Onset Sepsis

Authors :
Joseph R Hageman
Michael D. Schreiber
Alison Chu
Kenneth R. Alexander
Source :
NeoReviews. 13:e94-e102
Publication Year :
2012
Publisher :
American Academy of Pediatrics (AAP), 2012.

Abstract

Late onset sepsis infections contribute a significant proportion of the morbidity and mortality of hospitalized infants, especially in very low birth weight infants. Although it is fairly clear which infants are at higher risk of developing sepsis, it is less clear whether a standard for diagnostic evaluation exists and is being used consistently across institutions. In the current setting of changing epidemiology and emergence of antibiotic-resistant organisms, it is important to evaluate the antimicrobial agents used for empirical therapy and to emphasize the importance of antimicrobial stewardship. In addition, it is imperative to evaluate possible methods for prevention of these infections.

Details

ISSN :
15269906
Volume :
13
Database :
OpenAIRE
Journal :
NeoReviews
Accession number :
edsair.doi...........16b3f97bc42a83cced7adf27ed06875b
Full Text :
https://doi.org/10.1542/neo.13-2-e94