Heart failure in myocardial infarction with non-obstructive coronary arteries: predictors and prognosis

Funding Acknowledgements Type of funding sources: None. Introduction Heart failure (HF) is a frequent complication of acute coronary syndromes (ACS). However, 5-15% of patients admitted with suspected acute myocardial infarction have no significant lesions on coronary angiography (>50%). Contrary to initial beliefs, MINOCA is not a benign disease, given that mortality and incidence of MACE is similar to ACS. Objective To evaluate predictors and prognosis of HF in the setting of MINOCA. Methods Based on a multicenter retrospective study, data collected from admissions between 2013 and 2020. Patients (pts) without data on cardiovascular history or uncompleted clinical data were excluded. Pts were divided in 2 groups (G): GA – pts without HF; GB - pts with HF during hospitalization. Results HF occurred in 63 (5.2%) out of 1218 pts with MINOCA. There were no differences between G regarding gender (p=0.779). GB pts were older (72±10 vs 65±13, p1 (71.4% vs 6.3&, p2.0mg/dL) at admission (20.8% vs 4.8%, p400pg/ml) (100% vs 18.1%, p Logistic regression confirmed that KK>1 (p Conclusion As expected, HF in the setting of MINOCA is associated with poorer prognosis. Several features may help predict the HF occurrence during hospitalizations, allowing an earlier treatment.